Search Results - alexander+grenning

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Nitro-Driven Chemical Pathway for Producing Polyfunctionalized Aromatic Compounds

Develops Biaryl Compounds with Stable Axial Chirality This pathway for aromatic substitution provides a straightforward route to polyfunctionalized biaryl compounds with stable axial chirality. The rapid and controlled linking of functional groups and aromatic building blocks is a prominent pattern in developing new pharmaceuticals. In one common aromatic...

Published: 6/24/2024 | Inventor(s): Alexander Grenning, Vincent Vedovato

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Category(s): Technology Classifications > Engineering > Chemical, Technology Classifications > Agricultural > Therapeutics

Substituted Axially-Chiral Cannabinol Analogues for Non-Opioid Pain Management

Achieves the Bioactivity of THC with Improved Stability and Pharmaceutical PropertiesThese cannabinol analogues formulate analgesic drugs as an alternative to opioid medications. Due to the United States’ opioid crisis, many researchers investigate cannabinoid compounds as potential alternatives for pain management. An ongoing challenge in cannabinoid...

Published: 2/10/2023 | Inventor(s): Alexander Grenning, Primali Navaratne

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Category(s): Technology Classifications > Engineering > Chemical, Technology Classifications > Human Health Care > Therapeutics

Simple, Scalable Synthesis of Terpenoid Compounds for Pharmaceutical Research

Systematically Provides a Diverse Array of Polycyclic Terpene Cores for Use in Drug Design and DevelopmentStructurally complex terpenoid compounds provide access to a wide assortment of potential biological functions that can be exploited to develop pharmaceutical therapies. Despite recent efforts to increase efficiency within the pharmaceutical research...

Published: 6/27/2021 | Inventor(s): Alexander Grenning

Keywords(s): Natural Products, Terpene, Total synthesis

Category(s): Technology Classifications > Engineering > Chemical