Search Results - alejandro+villagra

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Novel Combination Immunotherapy Targeting CD47-SIRPα Axis and HDAC6 Inhibition
Recent advances in cancer therapy have increasingly focused on harnessing the body's immune system to combat cancer cells. Histone deacetylases (HDACs) play a critical role in the epigenetic regulation of gene expression by remodeling chromatin. HDAC inhibitors are recognized for their ability to induce cancer cell cycle arrest, differentiation,...
Published: 8/19/2024   |   Inventor(s): Alejandro Villagra, Maria del Mar Gracia Hernandez
Keywords(s):  
Category(s): Technology Classifications > Therapeutics > Small Molecules
Anti-inflammatory adoptive cell therapy using macrophages for enhanced tissue regeneration and wound healing
Patients dealing with organ transplants, autoimmune disorders, chronic wounds, ischemic injury, and other diseases that trigger inflammatory processes often lack effective treatment strategies. Macrophages are key cellular components of innate immunity with varying impacts on inflammation. M1 macrophages are pro-inflammatory, while M2 macrophages are...
Published: 9/11/2024   |   Inventor(s): Alejandro Villagra, Satish kumar Noonepalle, Maria del Mar Gracia Hernandez, Brett Shook
Keywords(s):  
Category(s): Technology Classifications > Therapeutics > Small Molecules