Search Results - alberto+bosque-pardos

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Transformative Nanoparticle-Based Therapy for HIV
HIV/AIDS remains a persistent global epidemic, affecting thousands of new individuals annually. A critical challenge in HIV treatment is the virus's ability to lie dormant in infected T cells, evading immune responses and existing antiretroviral therapies (ART). This latent HIV can reactivate unpredictably, leading to viral rebound and disease progression. Dr....
Published: 12/16/2024   |   Inventor(s): Rohan Fernandes, Preethi Balakrishnan, Anvitha Shri Ramanujam, Alberto Bosque-Pardos, Indra Sarabia, Carissa Stover
Keywords(s):  
Category(s): Technology Classifications > Therapeutics > Nanoparticles, Technology Classifications, Technology Classifications > Research Tools > Drug Screening
In vitro drug treatment to proliferate and activate effector cells for immunotherapy
­STAT5 SUMOylation inhibition increases CD4 and CD8 T-cell proliferation and and production of immune effector molecules in CD8 T-cells and NK (natural killer) cells. Both attributes address critical limiting factors in applying cell therapies to fighting cancers and pathogens. The difficulty of obtaining enough activated effector cells limits the...
Published: 9/11/2024   |   Inventor(s): Alberto Bosque-Pardos, Amanda Beatriz Rodrigues Barreto de Macedo, Eric Sorensen, Vicente Planelles
Keywords(s):  
Category(s): Technology Classifications > Therapeutics > Small Molecules