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Search Results - 4%5d
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Pyruvate Kinase M2 Activators for the Treatment of Cancer
NIH investigators have discovered a series of small compounds with the potential to treat a variety of cancers as well as hemolytic anemia. Contrary to most cancer medications, these molecules can be non-toxic to normal cells because they target a protein specific to the metabolic pathways in tumors, thus representing a significant clinical advantage...
Published: 10/28/2024
|
Inventor(s):
Min Shen
,
Craig Thomas
,
Douglas Auld
,
Matthew Boxer
Keywords(s):
[1
,
[b]
,
2
,
2-oxo-1
,
3
,
3-oxo-3
,
4]
,
4-dihydroquinoline-2H-benzo
,
4-tetrahydroquinoline-6-sulfonamides
,
ACTIVATORS
,
CB3CXX
,
CB3XXX
,
CBXXXX
,
CXXXXX
,
Human
,
Kinase
,
MOLECULE
,
Oxazine-7-sulfonamides
,
Patent Category - Chemistry
,
PYRUVATE
,
Small
,
Substituted
Category(s):
Collaboration Sought > Collaboration
,
Application > Therapeutics
,
TherapeuticArea > Oncology