Single-Step, Label-Free, Highly Accurate Analyte Detection

Description

This technology is two cutting-edge systems for single-step, label-free detection of analytes such as nucleic acids and certain drugs, particularly when the analyte exists in extremely low concentrations potentially replacing complex and expensive techniques such as qT-PCR.

The first system is a novel electrochemical method for simultaneous detection and quantification of multiple microRNAs as disease biomarkers within minutes. This sensor technology avoids time-consuming and labor-intensive sample pretreatments and complicated multi-step analysis procedures. It can be used as a high-throughput, point-of-care diagnostic tool. Currently used PCR tests can take hours to days for quantitative lab results or only provide yes/no answers in a shorter timeframe. The shorter tests have a high rate of false positive results.

The second system is an innovative electrochemiluminescence technique with a high signal/noise ratio and high specificity toward the chosen target analyte. It could be applied to directly detect compounds for which antibody/enzymes detection systems are not yet available, and as a readout system for assay/sensor development and drug development. The system is rapid, simple, and allows for sensitive and specific detection of analytes of interest at a low cost.

Benefits

Simple, Rapid & Low Cost –single-step and label-free platforms for detection in minutes, avoiding time-consuming and labor-intensive processing
Accurate – highly sensitive and specific, with minimal interference, for detecting a variety of analytes at very low sample concentrations
Flexible – adaptable design for diagnosing a variety of diseases or detection of compounds that currently lack detection reagents.