SAGE: A Low-Cost, High-Throughput Disease Agnostic Microfluidic Discovery Engine

This technology relates to a low-cost, high throughput microfluidic platform device which can help identify therapeutic compounds from a known agent, such as tuberculosis. Through a three-chip process, the invention can encapsulate, cultivate, screen and sort bacteria from a host of environmental microbes for bioactive natural products. The platform is disease agnostic, enabling a wide range of diagnostic capabilities, and provide equal if not better throughput than conventional liquid handling robots.

Background: 
New paradigms and technological approaches enabling rapid and informed disease management need to be implemented. In this respect, disease diagnostics that use microfluidic systems for pathogen detection offers a host of innovative and promising solutions, such as this low-cost, high throughput disease agnostic microfluidic detection device.  

Applications: 

  • Microfluidic platform
  • Microfluidic diagnostic device
  • Disease modeling


Advantages: 

  • Low-cost
  • Scalable
  • High-throughput
  • Disease agnostic
Patent Information: