Overview of Technology
IPRDNA Software for structural disorder calculations from confocal images of cells/tissues, enabling the detection and monitoring of diseases like cancer and Alzheimer's through molecular specific spatial structural alterations.
Background
Current methods for assessing structural disorder in biological cells and tissues often lack specificity and sensitivity. IPRDNA addresses this gap by utilizing a mesoscopic theory of physics to calculate molecular specific structural disorder through the Inverse Participation Ratio (IPR), providing a more accurate biomarker for disease progression.
Description of Technology
This software, developed on the MATLAB platform, calculates molecular specific structural disorder in biological cells and tissues using light localization methods. It leverages the average IPR to provide insights into spatial structural alterations, making it a valuable tool for monitoring diseases such as cancer and Alzheimer's. The software is at TRL 8, indicating it is a final product that has been field qualified through testing and demonstration.
Benefits
- Enhanced detection of molecular specific structural alterations
- Improved monitoring of disease progression
- Utilization of advanced light localization methods
- High accuracy in assessing structural disorder
- Final product ready for deployment.
Applications
- Medical diagnostics
- Cancer research
- Alzheimer's research
- Biomedical imaging
- Disease monitoring
- Academic research in biology and physics
Opportunity
Organizations involved in medical diagnostics, research institutions focusing on cancer and neurodegenerative diseases, and companies developing biomedical imaging technologies could greatly benefit from licensing and further developing the IPRDNA software.