Biological H2S / COS Donation by Thiocarbamates

1. Technology Overview 

The invention focuses on biological hydrogen sulfide (H₂S) and carbonyl sulfide (COS) donation using thiocarbamates. These compounds release COS, which is then converted to H₂S by hydrolysis or metabolism by carbonic anhydrase. The technology is currently in the development stage, with promising cross-industry applications in biological detection, imaging, and targeted drug delivery. 

2. Key Features and Benefits 

  • Slow-Releasing H₂S Donors: Provides sustained release of H₂S in response to external stimuli. 

  • Modular Donation Platform: Allows for modification of triggering moieties and release rates. 

  • Versatility: Applicable to various industries, including biotechnology and pharmaceuticals. 

  • Scalability: Synthesis processes can be scaled for larger quantities. 

  • Targeted Applications: Ideal for biological detection, imaging, and drug delivery systems. 

3. Applications and Market Focus 

  • Biological Detection: Use in detecting and imaging biological processes involving H₂S. 

  • Drug Delivery: Integration into targeted drug delivery systems. 

  • Biotechnology: Development of novel biological detection and imaging methods. 

  • Pharmaceutical Industry: Synthesis of complex organic molecules for various applications. 

  • Chemical Industry: Use in advanced synthesis techniques and equipment. 

4. Commercial Advantages 

  • Strategic Benefits: Provides reliable and scalable H₂S-releasing compounds for various applications. 

  • Implementation Advantages: Facilitates integration into existing biological detection and imaging systems. 

  • Market Positioning: Positions technology as a key enabler for advanced biological detection and drug delivery systems. 

  • Competitive Advantages: Offers slow-releasing H₂S donors and modular donation platform compared to existing methods. 

5. Partnership Opportunities 

  • Ideal Licensing Partners: Biotechnology firms, pharmaceutical companies, chemical industry leaders. 

  • Cross-Sector Partnership Benefits: Collaboration opportunities across biotechnology and pharmaceutical industries. 

  • Diverse Market Opportunities: Potential for global market expansion in regions with strong biotechnology and pharmaceutical industries. 

  • Collaborative Development: Opportunities for joint development of hybrid devices and custom synthesis services. 

 

Patent Information: