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C41 Analogs

This invention relates generally to neurodegenerative diseases and conditions, such as Alzheimer’s Disease, characterized with dysfunctional energetic function, unregulated microglia phagocytic activity and other related de-regulated biological functions. This invention further relates to methods and compositions for treating such neurodegenerative...

Published: 9/24/2024 | Inventor(s): Wei Wang, Rui Chang, Vijayan Ramachandran, Patrick Ronaldson

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Nutraceuticals, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Biologics

Tributyrin to Entain Human Circadian Rhythms and Improve Sleep in Individuals with Medical Disorders that can Increase Gut Permeability or Elevated Levels of Systemic Inflammation

This documents a new method of treatment for sleep improvements. Poor sleep is likely manifested by an underlying irregular circadian rhythm sleep disorder. A patient with a history of leaky gut syndrome and poor sleep took a commercially available oral short-chain fatty acid supplement, tributyrin, and documented improved sleep. This suggests a relationship...

Published: 1/10/2024 | Inventor(s): Sairam Parthasarathy

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Nutraceuticals, Technology Classifications > Healthcare Portfolios > Sleep Disorders

Enhancing Absorption of Dietary Compounds to Promote Health

This innovation is directed to oral co-administration of glucuronidase and polyphenols for reabsorption in the gut. Glucuronidase are enzymes that can be made or derived from any source such as bacteria, recombinant, species agnostic, and others. The inactive glucuronides are cleared from the body by secretion back into the gastrointestinal track where...

Published: 10/2/2023 | Inventor(s): Janet Funk

Keywords(s):

Category(s): Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Nutraceuticals, Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Healthcare Portfolios

Natural Compounds including Myrosinase to Treat Alzheimer's Diseases

This invention includes natural compounds for therapeutic use in patients suffering from Alzheimer’s Disease. The inventors have applied computational approaches to existing rich data sets generated by the Accelerating Medical Partnership-Alzheimer's disease consortia to discover novel targets. There are natural compounds which have shown...

Published: 7/6/2023 | Inventor(s): Rui Chang

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Biologics, Technology Classifications > Life Sciences > Nutraceuticals, Technology Classifications > Healthcare Portfolios > Neurology

Scalable Synthesis for Commercial Production of Carbohydrate-Based Molecular Scaffold Compounds for Direct Delivery of Drugs or Nutritional Supplements to the GI Tract

This invention provides a scalable synthesis method for commercial production (kilogram and greater) of novel carbohydrate-based molecular scaffold compounds for various therapeutic and diagnostic applications that have been and are being developed by UArizona inventors. Oral administration and targeted delivery of pro-drugs or other payloads, such...

Published: 3/12/2024 | Inventor(s): Eugene Mash, Jr.

Keywords(s):

Category(s): Technology Classifications > Materials > Processing, Technology Classifications > Healthcare Portfolios > Gastroenterology Disease, Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Life Sciences > Nutraceuticals

Carbohydrate-Based Surfactants and Methods of Production

This invention is a method to produce carbohydrate-based surfactants with repeated succession using a glycosylation promotor. Background: Current amphiphilic molecules, surfactants, emulsifiers, cleaning products and food additives are mostly made from synthetic surfactants. Commonly these surfactants are prepared from petroleum-based materials...

Published: 6/30/2023 | Inventor(s): Jeanne Pemberton, Robin Polt, Raina Maier, Ricardo Palos Pacheco

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Nutraceuticals