Search Results - technology+classifications+%3e+life+sciences+%3e+biomarkers

39 Results

Sort By:

Genomic and Proteomic Biomarkers of Disease Incidence

This invention is for a proteogenomic risk scoring system for a variety of disease incidences, specifically in Hispanic populations, particularly Type 2 diabetes. This system aims more specifically to utilize genomic, proteomic, and clinical risk scores to score patients with diabetes into high vs. low risk of progression of diabetic complications....

Published: 12/16/2024 | Inventor(s): Lawrence Mandarino, Dawn Coletta, Yann Klimentidis, Douglas Spegman

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Healthcare Portfolios > Diabetes, Metabolism, Endocrinology & Obesity

Factor XII(a) is a Biotarget for Treatment of Dilated Cardiomyopathy and Heart Failure

Researchers at the University of Arizona have identified a novel, previously unrecognized harmful role of coagulation factor, Factor XII (FXII) and/or activated coagulation factor XIIa (fXII(a)) in modulating the progression of dilated cardiomyopathy and heart failure development. They have proposed fXII(a) as a new biotarget to treat dilated cardiomyopathy...

Published: 12/4/2024 | Inventor(s): Guy Reed, Inna Gladysheva, Ryan Sullivan

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Heart and Vascular

Colorectal Cancer Prognostic/Prediction

This technology provides a gene score system to assess the effectiveness of antifibrotic treatments on colorectal cancer (CRC). By comparing gene expressions from colorectal cancer cells under two different types of mechanical conditioning, this system identifies specific gene signatures that correlate with an increased risk of metastasis and lower...

Published: 12/16/2024 | Inventor(s): Ghassan Mouneimne

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Research Tools

Myelin Breakdown Products as Plasma Biomarkers of Therapeutic Efficacy in the Acute Phase after Stroke

This invention pertains to the use of myelin breakdown products, such as lipids indicative of brain lipid catabolism, as plasma biomarkers for the diagnosis and prognosis of ischemic stroke (IS). Researchers discovered an acute signature of brain lipid catabolism in the plasma 24 hours after a stroke in mouse model research. Notably, a substantial proportion...

Published: 8/12/2024 | Inventor(s): Kristian Doyle, Danielle Becktel

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Life Sciences > Biomarkers

Arachidonic Acid Derivatives as Plasma Biomarkers of Chronic Inflammation After Stroke

This invention pertains to the use of arachidonic acid derivatives as plasma indicators for the diagnosis and prognosis of inflammation, including chronic inflammation, following ischemic stroke (IS). Researchers have identified novel plasma biomarkers indicative of neurodegeneration and inflammation in a mouse model of stroke, with particular emphasis...

Published: 8/12/2024 | Inventor(s): Kristian Doyle, Danielle Becktel

Keywords(s):

A Method for Label-Free, Non-Invasive Acquisition and Mapping of -Omics Data

This technology describes a novel process to generate -omics data, such as genomics, proteomics, and more, through optical imaging. The invention is intended to implement spatial imaging techniques to identify optical imaging markers that can be predictors of -omics. This technology has potential for usage in a variety of fields including in vivo or...

Published: 6/6/2024 | Inventor(s): Travis Sawyer, Suzann Duan, Thomas Graham Knapp

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics

Identification of Inhibitors of Trogocytosis to Treat Cancer

This innovation is the identification and isolation of small molecules to inhibit trogocytosis to prevent or slow cancer cell tumor growth. Researchers plan to develop cell lines transduced with lentivirus vectors that can be cocultured and the process of trogocytosis will result in cell fusion that will generate a luminescent signal. Selected small...

Published: 6/3/2024 | Inventor(s): Alfred Bothwell, Haley Marcarian, Anutr Sivakoses

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Biomarkers

Metabolic Screening Methods for Endometrial Cancer

Researchers at the University of Arizona employed cervicovaginal lavage sampling and a global untargeted metabolomic approach to identify potential biomarkers for endometrial cancer. The study's novel approach involved linking cervicovaginal metabolite levels to crucial tumor characteristics such as size, histological grade, and myometrial invasion,...

Published: 3/1/2024 | Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics

Methods for Guiding Treatments of Vulvovaginal Symptoms and Female Sexual Dysfunction

Multi-omics analysis of cervicovaginal samples has led to the identification of a specific immune mediators, metabolites, and bacteria that are associated with vulvovaginal and sexual health symptoms. These biomarkers hold the potential to be utilized in a non-invasive test that guides the treatment of vulvovaginal symptoms and female sexual dysfunction...

Published: 6/6/2024 | Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Healthcare Portfolios > Reproductive Health: Obstetrics & Gynecology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Therapeutics

Leukocyte Gene Expression Predicts Human Temporal Lobe Epilepsy Seizure Frequency

The leukocyte gene biomarkers presented here identify totally new and different genes whose expression predict temporal lobe epilepsy (TLE) seizure frequency. This seizure frequency prediction is a manifestation of the underlying pathophysiology of TLE disease states which have, heretofore, not been identified to have a dichotomized genetic basis. Targeting...

Published: 12/14/2023 | Inventor(s): Martin Weinand

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios, Technology Classifications > Life Sciences > Biomarkers

1 2 3 4