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Neck Cooling
Summary: A neck cooling device to selectively lower patient brain temperature after brain injury, providing protection from further injury. Technology overview: This neck cooling device is a noninvasive way to lower brain temperature after stroke, traumatic brain injury, heat exhaustion, or other brain conditions in order to protect the brain from...
Published: 3/11/2026   |   Inventor(s): Adam Sprouse-Blum
Keywords(s):  
Category(s): Technology Classifications > Medical Device, Technology Classifications > Biomedical
ARIA Laryngoscope
Summary: The ARIA (Automated Robotic Intubation Apparatus) laryngoscope is an improved design of the laryngoscope that allows for use in multiple settings and is expected to reduce time and attempts at laryngoscopy. Technology overview: This new design of laryngoscope improves upon traditional laryngoscopy, an airway exam, in several ways by having...
Published: 3/11/2026   |   Inventor(s): Borzoo Farhang
Keywords(s):  
Category(s): Technology Classifications > Biomedical
Composition and Methods for Preparing Orally Bioavailable Guanidine Prodrugs
THE CHALLENGE A major commercial hurdle in developing guanidine-based therapeutics lies in their poor oral bioavailability, which limits their effectiveness despite strong therapeutic potential. These compounds, while highly potent due to their ability to engage key molecular targets, struggle to reach the bloodstream when taken by mouth because of...
Published: 1/15/2026   |   Inventor(s): Webster Santos, Christopher Sibley, Kyle Dunnavant, Christopher Shrader, Ariel Burgio, Kevin Lynch, Yugesh Kharel
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Category(s): Technology Classifications > Biomedical
Activation of BMP3 to Treat Pulmonary Hypertension
THE CHALLENGE The major business challenge in addressing pulmonary arterial hypertension (PAH) lies in the urgent need for breakthrough therapies that go beyond symptom management to truly modify disease progression. Current drugs offer limited clinical benefit, are burdened by significant side effects, and fail to reverse the underlying biological...
Published: 10/27/2025   |   Inventor(s): Yassine Sassi, Aymen Halouani
Keywords(s):  
Category(s): Technology Classifications > Biomedical
Omni-mission Healthcare Vehicle (OHV)
A versatile healthcare solution designed to deliver specialized services to remote areas through a modular box truck. Technology Overview The Omni-mission Healthcare Vehicle (OHV) is a groundbreaking vehicle aimed at transforming mobile healthcare. It features a modular design that allows for the easy swap of healthcare equipment and furnishings to...
Published: 9/4/2025   |   Inventor(s): Michael Rosen
Keywords(s):  
Category(s): Technology Classifications > Biomedical, Technology Classifications > Engineering, Technology Classifications > Medical Device
Faster Output through Simplified Text Entry and Response (FOSTER)
An advanced communication software for individuals with ALS speeds text-to-speech input times and makes generating speech easier, enables real-time conversation, and allows for more effective interpersonal interaction. Technology Overview: Many individuals with amyotrophic lateral sclerosis (ALS) or other disorders that impair speech rely on assistive...
Published: 8/26/2025   |   Inventor(s): Noah Kolb, Noah Manz, Timothy Baugh, Varsha Pudi
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Category(s): Technology Classifications > Biomedical, Technology Classifications > Information Technology > Software & Data
Droplet-Based Single-Cell Epigenomic Assay
THE CHALLENGE A major challenge in single-cell DNA methylation profiling lies in the inefficiency and high cost of current methods, which rely on labor-intensive, plate- or tube-based workflows that are difficult to scale. These traditional approaches not only require multiple manual steps and expensive reagents but also suffer from significant DNA...
Published: 10/20/2025   |   Inventor(s): Chang Lu, Qiang Zhang
Keywords(s):  
Category(s): Technology Classifications > Biotechnology, Technology Classifications > Biomedical
Temporally Patterned Simulation Script/Algorithm/Software for the Treatment of Brain Injury, Neurodegenerative Diseases, and Psychiatric Disorders
THE CHALLENGE The key challenge associated with stimulation based neurological treatment lies in bridging the gap between cutting-edge neuroscience and the current limitations of commercial neuromodulation devices, which largely rely on outdated, fixed-frequency stimulation protocols. Despite mounting evidence that the brain’s response to therapy...
Published: 10/31/2025   |   Inventor(s): Michael Friedlander, Quentin Fischer, Djanenkhodja Kalikulov, Carrie Williams, Philip Baldwin, Gonzalo Di Prisco
Keywords(s):  
Category(s): Technology Classifications > Biomedical, Technology Classifications > Software
High-Efficiency CRISPR Editing in Mammalian Zygotes
THE CHALLENGE The major challenge in developing reliable gene editing solutions for livestock lies in delivering CRISPR reagents efficiently into mammalian zygotes without harming embryo viability, an issue that significantly limits scalability, consistency, and commercial viability. Traditional methods like microinjection are technically challenging,...
Published: 10/24/2025   |   Inventor(s): Fernando Biase
Keywords(s):  
Category(s): Technology Classifications > Biomedical, Technology Classifications > Biotechnology
Octopus-Mimetic Adhesives for Wet Surface Attachment
THE CHALLENGE The challenge in creating effective underwater adhesion systems lies in bridging a critical gap between advanced materials science and real-world usability, especially for industries like marine robotics, offshore maintenance, and biomedical handling. Traditional solutions either bond too permanently, require ideal flat surfaces, consume...
Published: 3/2/2026   |   Inventor(s): Michael Bartlett, Chanhong Lee
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Category(s): Technology Classifications > Biomedical, Technology Classifications > Biotechnology, Technology Classifications > Robotics
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