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High-Efficiency CRISPR Editing in Mammalian Zygotes
THE CHALLENGE The major challenge in developing reliable gene editing solutions for livestock lies in delivering CRISPR reagents efficiently into mammalian zygotes without harming embryo viability, an issue that significantly limits scalability, consistency, and commercial viability. Traditional methods like microinjection are technically challenging,...
Published: 7/10/2025   |   Inventor(s): Fernando Biase
Keywords(s):  
Category(s): Technology Classifications > Biomedical, Technology Classifications > Biotechnology
Octopus-Mimetic Adhesives for Wet Surface Attachment
THE CHALLENGE The challenge in creating effective underwater adhesion systems lies in bridging a critical gap between advanced materials science and real-world usability, especially for industries like marine robotics, offshore maintenance, and biomedical handling. Traditional solutions either bond too permanently, require ideal flat surfaces, consume...
Published: 7/3/2025   |   Inventor(s): Michael Bartlett, Chanhong Lee
Keywords(s):  
Category(s): Technology Classifications > Biomedical, Technology Classifications > Biotechnology, Technology Classifications > Robotics
Robotic Tail Used to Improve Performance and Stability of Mobile Robots
THE CHALLENGE Natural and man-made disasters are becoming more and more commonplace. As these disasters increase in number, so does the need for, and risk to, first responders who search through rubble and rescue survivors. In response to these increased risks, legged mobile robots have emerged as a first response option as they can maneuver over...
Published: 6/30/2025   |   Inventor(s): Pinhas Ben-Tzvi, Wael Saab, William Rone
Keywords(s):  
Category(s): Technology Classifications > Engineering, Technology Classifications > Biomedical, Technology Classifications > Biotechnology, Technology Classifications > Electronics, Technology Classifications > Medical Devices
Genomic and Proteomic Biomarkers for Heifer Fertility
THE CHALLENGE Fertility is a critical factor in livestock breeding, directly impacting the productivity and economic viability of beef and dairy operations. Each year, more than 750,000 beef heifers and 210,000 dairy heifers fail to produce calves despite multiple breeding attempts using artificial insemination or bull exposure. These sub-fertile or...
Published: 6/25/2025   |   Inventor(s): Fernando Biase
Keywords(s):  
Category(s): Technology Classifications > Biomedical
Vascular Integrity Preserved by “VasoPlex” Post Heart Attack
A method of preserving cardiovascular integrity to limit long-term damage after myocardial infarction and other ischemic events Background: Compromised distal myocardial perfusion is commonly observed in 25-30% of patients with acute myocardial infarction (MI) despite action to restore blood flow in local lay vessels via thrombolytics and PCI/stenting....
Published: 5/22/2025   |   Inventor(s): Jeffrey Spees, Benjamin Liebman
Keywords(s):  
Category(s): Technology Classifications > Biomedical
Knee Monitoring Device for Surgical Rehabilitation and Maximizing Sports Performance
The system can be used to allow clinicians to monitor patients’ at-home progress and compliance with rehab protocols after knee surgery Background: Current technologies that can be deployed remotely only measure steps taken and/or range of motion to monitor post-surgical rehabilitation or performance. Technologies that can accurately measure...
Published: 5/21/2025   |   Inventor(s): Ryan McGinnis, Reed Gurchiek
Keywords(s):  
Category(s): Technology Classifications > Biomedical, Technology Classifications > Medical Device
Hemodialysis Filter Rotor
Heparin-free hemodialysis is usually obligatory in immediate post-operative states, bleeding diathesis and in critically ill patients. Conventionally, this is achieved through normal saline flushes and regional citrate anticoagulation, however, dialysis filters often clot requiring extra saline flushes and/or anticoagulation drugs, including, heparin....
Published: 5/21/2025   |   Inventor(s): Macaulay Onuigbo, Adam Locke
Keywords(s):  
Category(s): Technology Classifications > Biomedical
Tunable Stack Architecture for Photonic Crystal OLEDs
These OLED vertical stacks are low cost, durable and applications in flexible displays, light panels and spectroscopy sensors Background: Organic light-emitting diode (OLED) technology brings the promise of sharper displays at lower cost. This sharpness arises from the fact that conventional LEDs leak a little light when displaying black, degrading...
Published: 5/21/2025   |   Inventor(s): Matthew White, David Allemeier
Keywords(s):  
Category(s): Technology Classifications > Biomedical, Technology Classifications > Engineering
Preparations of Primary Phosphines
A clean phosphine synthesis method that circumvents the use of toxic reagents, uses industrially common hydrogen and produces no waste Background: Primary phosphines are highly versatile precursors and are used as commercial reagents in industries such as pharmaceutical manufacturers, agriculture (pesticides), and materials science industries (semiconductors)....
Published: 5/21/2025   |   Inventor(s): Rory Waterman, Brandon Ackley
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Category(s): Technology Classifications > Biomedical, Technology Classifications > Agriculture, Technology Classifications > Engineering
Nanocage Sensors
The molecular nanocage concept can verify the purity and authenticity of agricultural products and could detect environmental contaminants Background: Increasing globalization and competition has created large economic incentives to commit food fraud by adding adulterants, fillers, or other inauthentic ingredients to agricultural products. Consequently,...
Published: 5/21/2025   |   Inventor(s): Jianing Li, Severin Schneebeli, Mona Sharafi
Keywords(s):  
Category(s): Technology Classifications > Agriculture, Technology Classifications > Biomedical
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