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Search Results - sherry+chemler
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Antiproliferative Betti Bases and Prodrugs Thereof
Betti base drugs and prodrugs optimized to enhance their antiproliferative activity through inhibition of MDM2, MDMX, p53, E3 ligase and FTH1. Background: Betti bases are a family of small organic molecules composed of phenolic or hydroxyarl benzylic amine derivatives. These molecules have established antiproliferative effects on various cancer cell...
Published: 8/13/2024
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Inventor(s):
Sherry Chemler
,
Xinjiang Wang
,
Samuel Galster
,
Rati Lama
Keywords(s):
Featured
,
Technologies
Category(s):
Campus > University at Buffalo
,
Technology Classifications > Biomedical Science and Engineering
,
Technology Classifications > Healthcare
,
Technology Classifications > Therapeutics and Vaccines