Search Results - research+area+%3e+immunobiology+and+inflammation

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IRF4-Engineered T Cells Induce T Cell Function As a Treatment Strategy for Solid Tumors
Asset/Technology Type New Therapeutic Strategy Description of Invention The invention includes compositions and methods of delivering therapeutic anti-tumor T cells by forcing them to overexpress interferon regulatory factor (IRF4) as a treatment for various solid tumors, including but not limited to melanoma, lymphoma, and colon cancer. The inventors...
Published: 4/11/2025   |   Inventor(s): Wenhao Chen, Xian Li
Keywords(s):  
Category(s): Clinical Area > Transplantation, Clinical Area > Cancer, Clinical Area > Metabolic Disease, Inflammation, and Immunology, Research Area > Cancer, Research Area > Immunobiology and Inflammation, Technology Classifications > Therapeutic > Cell and Gene Therapies
Modulating the AIBP-CAV1-VEGFR3 axis to treat lymphatic disorders
This invention is a method of promoting lymphangiogenesis in order to treat lymphatic disorders, namely lymphedema and Alzheimer’s disease (AD). VEGFC-induced VEGFR3 signaling is the major driver of lymphangiogenesis, however the distinct molecular mechanisms determining how VEGFR3 signaling controls lymphatic endothelial cell (LEC) fate remains...
Published: 3/12/2024   |   Inventor(s): Longhou Fang, Jun-dae Kim
Keywords(s):  
Category(s): Clinical Area > Metabolic Disease, Inflammation, and Immunology, Clinical Area > Neurology, Clinical Area > Cardiovascular, Research Area > Heart and Vascular, Research Area > Immunobiology and Inflammation, Research Area > Neurology and Neurosurgery, Technology Classifications > Therapeutic > Cell and Gene Therapies, Technology Classifications > Therapeutic > Small Molecules, Technology Classifications > Therapeutic > Biologics
Biomimetic Anti-Inflammatory Membrane for Chronic Wound Healing
The invention is a collagen membrane functionalized with mannose for the treatment of chronic wounds. Due to its mannose coating, this membrane is able to induce the polarization of macrophages to an anti-inflammatory state, resulting in less overall inflammation during wound repair. Stage of Development In vitro data: Membrane synthesis and characterization...
Published: 3/12/2024   |   Inventor(s): Ennio Tasciotti, Francesca Taraballi
Keywords(s):  
Category(s): Technology Classifications > Medical Device > Implantables, Clinical Area > Metabolic Disease, Inflammation, and Immunology, Research Area > Immunobiology and Inflammation, Research Area > Regenerative Medicine