Search Results - renal+%2f+kidney

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Novel Therapy to Prevent Kidney Transplant Rejection
Advantages First-in-class mechanism: Only known PPP1R3G/PP1γ inhibitor—differentiated from all RIPK1/RIPK3 competitors Upstream targeting: Acts before RIPK1 activation for potentially improved selectivity Validated efficacy: Demonstrated reduction in necroptosis markers (p-RIP1, p-RIP3, p-MLKL) Large unmet need: No approved DGF prevention...
Published: 2/11/2026   |   Updated: 1/12/2026   |   Inventor(s): Lei Wang, Zhigao Wang, Jianfeng Cai
Keywords(s): Organ Transplantation, Renal / Kidney
Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Chemistry, Technology Classifications > Medical > Therapeutics
Reducing Ischemic Kidney Injury Through Synchronization Modulation Electric Field (SMEF)
Advantages SMEF enables ATP regeneration under ischemic conditions Non-invasive, broad-spectrum applicability to multiple cell and tissue types Enhances organ viability during transplantation Broad Applicability: mechanism is relevant to other ischemic injuries (e.g., heart, brain, liver), opening doors to multi-organ applications Summary Kidney...
Published: 8/8/2025   |   Updated: 8/8/2025   |   Inventor(s): Wei Chen, Ruisheng Liu
Keywords(s): Organ Transplantation, Renal / Kidney
Category(s): Technology Classifications > Medical > Cell & Tissue Engineering