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Quantitative analysis of tRNA abundance and modifications by nanopore RNA sequencing.
Transfer RNAs (tRNAs) play a central role in protein translation. Studying them has been difficult in part because a simple method to simultaneously quantify their abundance and chemical modifications is lacking. Here we introduce Nano-tRNAseq, a nanopore-based approach to sequence native tRNA populations that provides quantitative estimates of both...
Published: 9/29/2023   |   Inventor(s): Eva Novoa, Morghan Lucas, Leszek Pryszcz, Rebeca Medina Azmecua
Keywords(s): Algorithms, Bioinformatics, Biomarkers, Diagnostics, Liquid Biopsy, Oncology
Category(s): Methodology, Software & Algorithms