Search Results - medical+devices+%26+diagnostics

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COLD SINTERED MXENE CERAMICS
PAGE SUMMARY This technology introduces a novel method for integrating 2D materials into ceramics without high-temperature degradation, enhancing their electrical and mechanical properties. It was jointly developed by leading researchers Yury Gogotsi at Drexel University and Clive Randall at Penn State University and is available for licensing. Nanocomposites...
Published: 12/5/2024   |   Inventor(s): Yury Gogotsi, Babak Anasori, Benjamin Legum, Pavel Lelyukh, Jing Guo, Ke Wang, Clive Randall
Keywords(s):  
Category(s): Materials & Chemicals, Energy, Electrical Engineering & Electronics, Medical Devices & Diagnostics, Medical Devices & Diagnostics > MDD: Implantable/Prosthetic Devices, Materials & Chemicals > M-C: MXenes, Materials & Chemicals > M-C: Chemicals and Processes, Energy > Energy: Energy Storage, Electrical Engineering & Electronics > EE: Components, Electrical Engineering & Electronics > EE: Electronic Devices
Biomimetic aggrecan injection for lower back pain treatment
PAGE TITLE Overview PAGE SUMMARY Proteoglycans (PGs) are a major building block and a hydrating agent in the extracellular matrix, which maintains structural organization of cells within tissues. PGs retain water and regulate flow of minerals and other nutrients, lubricate and provide mechanical support to the tissues. The combination of PGs and...
Published: 7/16/2024   |   Inventor(s): Michele Marcolongo, Caroline Schauer, Sumona Sarkar, Edward Vresilovic, Benjamin Jackson
Keywords(s): Aggrecan, Biomaterial, Biomimetic, Degenerative disc disease, Injectable, Lower back pain, Minimally Invasive, Spine
Category(s): Life Sciences, Medical Devices & Diagnostics
Non-invasive quantitative monitor of depth of anesthesia and sedation
PAGE TITLE Overview PAGE SUMMARY Drexel researchers have developed a non-invasive device for quantitative, real-time monitoring of the depth of anesthesia both during general anesthesia in surgery and sedation in endoscopy and colonoscopy procedures. The device uses functional near-infrared (fNIR) spectroscopy to measure physiological parameters...
Published: 7/16/2024   |   Inventor(s): Kambiz Pourrezaei, Kurtulus Izzetoglu, Banu Onaral, Jay Horrow, Scott Bunce, Meltem Izzetoglu
Keywords(s): NIR - near infrared
Category(s): Life Sciences, Medical Devices & Diagnostics
Low-cost manufacturing of highly sensitive label-free molecular detection substrates
PAGE TITLE Overview PAGE SUMMARY Label-free detection and characterization of molecules is an important tool for detecting a composition of a substance, be it a water, soil, chemical product or biological sample. Its main advantage is the ability to measure quantities of different molecules without knowing their identity in advance. Examples...
Published: 7/16/2024   |   Inventor(s): Som Tyagi, Kambiz Pourrezaei
Keywords(s):  
Category(s): Life Sciences, Medical Devices & Diagnostics, Physical Sciences, Mechanical & Civil Engineering
enAble Games
PAGE TITLE Company Background PAGE SUMMARY enAble Games was created to offer an innovative suite of active video games (AVG) to support physical therapy for children and adults with cerebral palsy and other neuromuscular conditions. It was founded by Drexel University professors in Digital Media and Physical Therapy bringing their knowledge and...
Published: 5/16/2024   |   Inventor(s):  
Keywords(s):  
Category(s): Startup Companies, Life Sciences, Medical Devices & Diagnostics, Computing, Software, Analytics & Information Technology
Telomere assay for the detection of alternative lengthening of telomere (ALT) activity in cells
PAGE TITLE Overview PAGE SUMMARY Executive Statement: A unique tool for distinguishing cancer cells based on telomere maintenance mechanisms, providing potential biomarkers for cancer subtypes and therapeutic responses. Description: This technology provides detailed telomere profiling from individual chromosomes, capable of differentiating...
Published: 6/28/2024   |   Inventor(s): Ming Xiao
Keywords(s):  
Category(s): Life Sciences, Medical Devices & Diagnostics, Medical Devices & Diagnostics > MDD: Diagnostic Tests, Pharmaceuticals & Therapeutics > Pharma: Gene Therapy, Pharmaceuticals & Therapeutics > Pharma: Cellular Therapy, Pharmaceuticals & Therapeutics > Pharma: Genome Engineering, Research Tools & Materials
Quantification of On-off target gene editing by optical mapping
PAGE TITLE Overview PAGE SUMMARY Executive Statement: A revolutionary methodology for quantifying on-target and off-target gene editing activity using CRISPR-Cas9 and optical mapping. Description: This technology comprises a single-molecule optical mapping strategy using CRISPR-Cas9 to fluorescently label the modified genes. The method involves...
Published: 6/28/2024   |   Inventor(s): Ming Xiao, Yilin Wang, Lahari Uppuluri
Keywords(s):  
Category(s): Life Sciences, Medical Devices & Diagnostics, Medical Devices & Diagnostics > MDD: Diagnostic Tests, Research Tools & Materials, Pharmaceuticals & Therapeutics > Pharma: Cellular Therapy, Pharmaceuticals & Therapeutics > Pharma: Gene Therapy, Pharmaceuticals & Therapeutics > Pharma: Genome Engineering
Multicolor whole-genome mapping for genetic analysis
PAGE TITLE Overview PAGE SUMMARY Executive Statement: A novel method for precise genome mapping and sequencing using Cas9-mediated labeling within nanochannels. Description: This technology is a method for mapping a whole genome using a universal multi-color mapping strategy in nanochannels that combines a conventional sequence-motif labeling...
Published: 6/20/2024   |   Inventor(s): Ming Xiao, Lahari Uppuluri
Keywords(s):  
Category(s): Life Sciences, Medical Devices & Diagnostics, Medical Devices & Diagnostics > MDD: Diagnostic Tests, Pharmaceuticals & Therapeutics > Pharma: Cellular Therapy, Pharmaceuticals & Therapeutics > Pharma: Gene Therapy, Pharmaceuticals & Therapeutics > Pharma: Genome Engineering, Research Tools & Materials
Single molecule real-time long DNA mapping and sequencing
PAGE TITLE Overview PAGE SUMMARY Executive Statement: The invention offers an innovative way to immobilize and optically map/sequence oligonucleotides on a micropatterned substrate for efficient large-scale genomic assembly. Description: This technology presents a method for immobilizing and linearizing oligonucleotides on a micropatterned...
Published: 6/20/2024   |   Inventor(s): Ming Xiao, Dharma Varapula, Eric LaBouff, Moses (hongseok) Noh
Keywords(s):  
Category(s): Medical Devices & Diagnostics, Computing, Software, Analytics & Information Technology > Computing: Bioinformatics, Medical Devices & Diagnostics > MDD: Diagnostic Tests, Life Sciences, Pharmaceuticals & Therapeutics > Pharma: Cellular Therapy, Pharmaceuticals & Therapeutics > Pharma: Gene Therapy, Pharmaceuticals & Therapeutics > Pharma: Genome Engineering, Research Tools & Materials
CRISPR-Cas9 Labeling of Human Genomic DNA for Telomere Length Measurement
PAGE TITLE Overview PAGE SUMMARY Executive Statement: An innovative method for the precise detection and measurement of individual telomere lengths that can be correlated to specific chromosomes. Description: This technology provides a method for detecting the length of individual telomeres in genomic DNA using a unique combination of guide...
Published: 4/6/2024   |   Inventor(s): Ming Xiao, Jennifer McCaffrey
Keywords(s):  
Category(s): Medical Devices & Diagnostics, Medical Devices & Diagnostics > MDD: Diagnostic Tests, Life Sciences, Pharmaceuticals & Therapeutics > Pharma: Cellular Therapy, Pharmaceuticals & Therapeutics > Pharma: Gene Therapy, Pharmaceuticals & Therapeutics > Pharma: Genome Engineering, Pharmaceuticals & Therapeutics > Pharma: Oncology
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