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Methods and composition for gene editing at the transferrin locus
Gene editing toolbox Cas-9-based proprietary tools for gene editing, better production and efficient CAR-T cells, and/or transfer of therapeutic proteins across the blood-brain barrier Shutterstock : 2166283693 UNMET NEED Pediatric metabolic diseases. There is currently no approved long-term therapy or cure for several diseases such as type...
Published: 6/19/2025   |   Inventor(s): Jean-François Rivest, Yannick Doyon
Keywords(s): Innovation
Category(s): Secteurs > Sciences de la vie, Sectors > Life sciences, Sustainable Development Goals > Goal 03: Good Health and Well-Being, Objectifs de Développement Durable > ODD 03 : Bonne santé et bien-être, Applications > Soins et santé > Traitement > Biotechnologies, English Applications > Health and care > Treatment > Biotechnologies-T
Layer-by-layer modified lipid nanoparticles for enhanced gene and drug delivery and applications thereof
LbL MODIFIED LNPs - GENE & DRUG DELIVERY New layer-by-layer (LbL) assembled Lipid nanoparticles (LNPs) platform for high biomolecule loading, staged release, adequate protection of cargo and modulated targeting property. Shutterstock : 2166283693 UNMET NEED The development of nanocarriers capable of encapsulating, targeting, and delivering...
Published: 6/19/2025   |   Inventor(s): Chun Yang, Xavier Banquy, Victor Passos Gibson, Houda Tahiri, Pierre Hardy
Keywords(s): Innovation
Category(s): Objectifs de Développement Durable > ODD 03 : Bonne santé et bien-être, Sustainable Development Goals > Goal 03: Good Health and Well-Being, Secteurs > Sciences de la vie, Sectors > Life sciences, Applications > Soins et santé > Traitement > Biotechnologies, English Applications > Health and care > Treatment > Biotechnologies-T
Poly (monoglycerol acrylate) - PMGA
POLY (MONOGLYCEROL ACRYLATE) New alternative to PEG in lipid nanoparticles (LNP) Shutterstock : 2203572829 UNMET NEED Poly (ethylene glycol) (PEG) is widely used in pharma to 1) prepare bioconjugates and 2) generate lipid nanoparticles (LNPs). In LNPs that contain nucleic acids, PEG-lipids facilitate the preparation of stable colloids, but...
Published: 6/19/2025   |   Inventor(s): Sabrina Roussel, Philippe Grenier, Nicolas Bertrand
Keywords(s): Innovation
Category(s): Applications > Soins et santé > Traitement > Biotechnologies, English Applications > Health and care > Treatment > Biotechnologies-T, Secteurs > Sciences de la vie, Secteurs > Sciences et génie, Sectors > Life sciences, Sectors > Science and Technologies, Sustainable Development Goals > Goal 03: Good Health and Well-Being, Objectifs de Développement Durable > ODD 03 : Bonne santé et bien-être