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Search Results - clinical+area+%3e+transplantation
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IRF4-Targeted Therapies for Cancer, Transplant Rejection, and Autoimmune Disorders
This invention is a method of depleting or over-expressing the transcription factor, interferon regulatory factor 4 (IRF4), in T cells as therapeutic strategy for conditions which are highly regulated by the immune system. The inventors have established that IRF4 represses PD-1, Helios, and other molecules associated with T cell function, representing...
Published: 10/8/2024
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Inventor(s):
Wenhao Chen
,
Xian Li
Keywords(s):
Category(s):
Technology Classifications > Therapeutic > Cell and Gene Therapies
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Clinical Area > Transplantation
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Clinical Area > Cancer
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Clinical Area > Metabolic Disease, Inflammation, and Immunology
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Research Area > Cancer
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Research Area > Immunobiology and Inflammation