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Multifunctional iron chelators to combat antibiotic resistance and enable bacterial imaging
Deferasirox derivatives, such as ExPh and ExBT, are designed to chelate iron and inhibit antibiotic-resistant bacteria like MRSA and VRE. They exhibit unique fluorescent properties for bacterial imaging, offering both therapeutic and diagnostic capabilities. Background Antibiotic resistance is a growing public health concern, driven by the rapid evolution...
Published: 10/14/2024   |   Inventor(s): Jonathan Sessler, Adam Sedgwick, James Brewster, II, Axel Steinbrück
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Category(s): Life sciences > Therapeutics > Formulation, Life sciences > Therapeutics